What is epigenetics and how does it relate to cancer?
Epigenetics is the study of changes in gene expression that do not involve alterations to the DNA sequence itself. These changes can be influenced by environmental factors and lifestyle choices. In cancer, epigenetic alterations can contribute to the development and progression of tumors by affecting gene expression patterns.
How do epigenetic changes impact tumor suppression?
Epigenetic changes can silence tumor suppressor genes, which are responsible for regulating cell growth and preventing the formation of tumors. When these genes are turned off, cells can divide uncontrollably and lead to the development of cancer.
Can epigenetic therapies be used to treat cancer?
Researchers are exploring the use of epigenetic therapies as a potential treatment for cancer. These therapies aim to reverse the epigenetic changes that drive tumor growth and restore normal gene expression patterns. While still in early stages of development, epigenetic therapies show promise as a new approach to cancer treatment.
What are some examples of epigenetic modifications that are associated with cancer?
Some examples of epigenetic modifications linked to cancer include DNA methylation, histone modifications, and non-coding RNA regulation. These changes can alter gene expression and contribute to the development of tumors by promoting cell proliferation, inhibiting cell death, and enhancing metastasis.
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